Hfq Virulence Regulation in Enterohemorrhagic 1 Escherichia coli O 157 : H 7 Strain 86 - 24 2 3 Running title : Hfq Virulence Regulation in EHEC Strain 86 - 24
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Hfq Virulence Regulation in Enterohemorrhagic 1 Escherichia coli O157:H7 Strain 86-24 2 3 Running title: Hfq Virulence Regulation in EHEC Strain 86-24 4 5 Melissa M. Kendall, Charley C. Gruber, David A. Rasko, David T. Hughes, & Vanessa 6 Sperandio 7 1 Department of Microbiology, University of Texas Southwestern Medical Center at Dallas, 8 Dallas, Texas, 5323 Harry Hines Blvd., 75390-9048, U.S.A. 9 2 Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, 10 Dallas, Texas, 5323 Harry Hines Blvd., 75390-9048, U.S.A. 11 3 Institute for Genome Sciences, Department of Microbiology & Immunology, University of 12 Maryland School of Medicine, BioPark Building II, 801 West Baltimore Street, Suite 619, 13 Baltimore, MD 21201 14 15 ** Correspondence should be sent to: 16 Vanessa Sperandio, Ph.D. 17 University of Texas Southwestern Medical Center, Dept. of Microbiology 18 5323 Harry Hines Blvd. Dallas, TX 75390-9048, USA 19 Telephone: 214-633-1378; Fax: 214-648-5905 20 Email: [email protected] 21 For Express Mail: 22 6000 Harry Hines Blvd. NL4.140, Dallas, TX 75235, USA 23 24 Copyright © 2011, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.06141-11 JB Accepts, published online ahead of print on 7 October 2011
منابع مشابه
Hfq virulence regulation in enterohemorrhagic Escherichia coli O157:H7 strain 86-24.
Enterohemorrhagic Escherichia coli O157:H7 (EHEC) causes bloody diarrhea and hemolytic-uremic syndrome. EHEC encodes the sRNA chaperone Hfq, which is important in posttranscriptional regulation. In EHEC strain EDL933, Hfq acts as a negative regulator of the locus of enterocyte effacement (LEE), which encodes most of the proteins involved in type III secretion and attaching and effacing (AE) les...
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